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2. TCH (chemotherapy) - Wikipedia

   en.wikipedia.org/wiki/TCH_(chemotherapy)

   TCH is a chemotherapy regimen consisting of Taxotere (docetaxel), carboplatin and Herceptin (trastuzumab), which is used to treat breast cancer. References

3. Triple-negative breast cancer - Wikipedia

   en.wikipedia.org/wiki/Triple-negative_breast_cancer

   Triple-negative is sometimes used as a surrogate term for basal-like. [2] Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers.

4. Chemotherapy regimen - Wikipedia

   en.wikipedia.org/wiki/Chemotherapy_regimen

   breast cancer ("TAC" can also refer to tetracaine-adrenaline-cocaine, used as local anesthetic) TAD tioguanine, cytarabine (ara-C), daunorubicin: acute myeloid leukemia: TC or CT docetaxel (Taxotere), cyclophosphamide: breast cancer: TCH: docetaxel (Taxotere), carboplatin, trastuzumab (Herceptin) breast cancer with positive HER2/neu receptor TCHP

5. Docetaxel - Wikipedia

   en.wikipedia.org/wiki/Docetaxel

   Docetaxel (DTX or DXL), sold under the brand name Taxotere among others, is a chemotherapy medication used to treat a number of types of cancer. [6] This includes breast cancer, head and neck cancer, stomach cancer, prostate cancer and non-small-cell lung cancer. [7] It may be used by itself or along with other chemotherapy medication. [6]

6. Breast cancer classification - Wikipedia

   en.wikipedia.org/wiki/Breast_cancer_classification

   Conversely, triple negative cancer (i.e. no positive receptors), lacking targeted treatments, now has a comparatively poor prognosis. [42] [43] Androgen receptor is expressed in 80-90% of ER+ breast cancers and 40% of "triple negative" breast cancers. Activation of androgen receptors appears to suppress breast cancer growth in ER+ cancer while ...

7. Taxane - Wikipedia

   en.wikipedia.org/wiki/Taxane

   Mechanism of action of taxanes. The principal mechanism of action of the taxane class of drugs is the disruption of microtubule function. Microtubules are essential to cell division, and taxanes stabilize GDP-bound tubulin in the microtubule, thereby inhibiting the process of cell division as depolymerization is prevented.