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Lurasidone, sold under the brand name Latuda among others, is an atypical antipsychotic medication used to treat schizophrenia and bipolar depression. [2] It is taken by mouth. Common side effects include sedation, indigestion, nausea, and insomnia. At higher dosages, there is an increased risk for restlessness and mild movement problems. [2]
These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Common side effects include tremors, tics, dizziness, dry mouth, restlessness, nausea, and mild sedation. [6] [7] Although it can also cause weight gain, the risk is much lower than for other atypical antipsychotics. [8] How it works is not entirely clear but is believed to involve effects on serotonin and dopamine in the brain. [5]
The side effects reportedly associated with the various atypical antipsychotics vary and are medication-specific. Generally speaking, atypical antipsychotics are widely believed to have a lower likelihood for the development of tardive dyskinesia than the typical antipsychotics. However, tardive dyskinesia typically develops after long-term ...
While atypical antipsychotics appear to have a lower rate of movement problems as compared to typical antipsychotics, risperidone has a high risk of movement problems among the atypicals. [46] [47] Atypical antipsychotics, however, are associated with a greater amount of weight gain and other metabolic side effects. [48] [47]
Aribit (Aripiprazole) tablets. Aripiprazole, sold under the brand names Abilify and Aristada, among others, is an atypical antipsychotic [8] primarily used in the treatment of schizophrenia, bipolar disorder, and irritability associated with autism spectrum disorder; [8] other uses include as an add-on treatment for major depressive disorder and tic disorders. [8]
It is debatable whether, as a class, typical or atypical antipsychotics are more effective. [24] Both have equal drop-out and symptom relapse rates when typicals are used at low to moderate dosages. [25] While quetiapine has lower rates of extrapyramidal side effects, there is greater sleepiness and rates of dry mouth. [23]
Clotiapine (Entumine) is an atypical antipsychotic [2] of the dibenzothiazepine chemical class. [3] It was first introduced in a few European countries (namely, Belgium, Italy, Spain and Switzerland), Argentina, Taiwan and Israel in 1970.