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  2. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    The magnitude of AST and ALT elevations vary depending on the cause of the increase, such as intensity of recent muscular exertion or type of hepatocellular injury. The following refer to the " upper reference limit " (URL), also known as the "upper limit of normal" (ULN), which depend on the source and are typically 40-50 U/L (0.67-0.83 μkal ...

  3. Alanine transaminase - Wikipedia

    en.wikipedia.org/wiki/Alanine_transaminase

    Fluctuation of ALT levels is normal over the course of the day, and they can also increase in response to strenuous physical exercise. [ 9 ] When elevated ALT levels are found in the blood, the possible underlying causes can be further narrowed down by measuring other enzymes.

  4. AST/ALT ratio - Wikipedia

    en.wikipedia.org/wiki/AST/ALT_ratio

    Most causes of liver cell injury are associated with a greater increase in ALT than AST, but an AST/ALT ratio of 2:1 or greater is suggestive of alcoholic liver disease, particularly in the setting of an elevated gamma-glutamyl transferase. [4]

  5. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    When ALT rises to more than 500 IU/L, causes are usually from the liver. It can be due to hepatitis, ischemic liver injury, and toxins that causes liver damage. The ALT levels in hepatitis C rises more than in hepatitis A and B. Persistent ALT elevation more than 6 months is known as chronic hepatitis.

  6. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.

  7. Hemolytic jaundice - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_jaundice

    The underlying causes of hemolytic jaundice, as its name suggests, are disorders associated with hemolysis. Such disorders are manifold and the common causes include: Blood smear of a patient with sickle cell disease. The characteristic sickle-shaped appearance of red blood cells can be observed.

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  9. Budd–Chiari syndrome - Wikipedia

    en.wikipedia.org/wiki/Budd–Chiari_syndrome

    Budd Chiari syndrome may present with elevated liver enzymes; alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are often elevated in the acute phase and then decrease over time as chronic liver disease develops. [2]