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Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. [1] Isosorbide dinitrate was first written about in 1939. [3] It is on the World Health Organization's List of Essential Medicines. [4] Isosorbide dinitrate is available as a generic medication. [1] [5] A long-acting form exists. [1]
The procedure starts with 100 g graphite and 50 g of sodium nitrate in 2.3 liters of sulfuric acid at 66 °C which is then cooled to 0 °C. 300 g of potassium permanganate is then added to the solution and stirred. Water is then added in increments until the solution is approximately 32 liters.
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration.
The nitrite ion has the chemical formula NO − 2.Nitrite (mostly sodium nitrite) is widely used throughout chemical and pharmaceutical industries. [1] The nitrite anion is a pervasive intermediate in the nitrogen cycle in nature.
Solutions of lead nitrate can be used to form co-ordination complexes. Lead(II) is a hard acceptor ; it forms stronger complexes with nitrogen and oxygen electron-donating ligands. For example, combining lead nitrate and pentaethylene glycol (EO 5 ) in a solution of acetonitrile and methanol followed by slow evaporation produced the compound ...
Lead styphnate (lead 2,4,6-trinitroresorcinate, C 6 HN 3 O 8 Pb ), whose name is derived from styphnic acid, is an explosive used as a component in primer and detonator mixtures for less sensitive secondary explosives.
The compound is a salt with separated hydroxyammonium and nitrate ions. [2] Hydroxylammonium nitrate is unstable because it contains both a reducing agent (hydroxylammonium cation) and an oxidizer , [3] the situation being analogous to ammonium nitrate. It is usually handled as an aqueous solution with small amount of nitric acid as a stabilizer.
The decomposition of ammonium nitrate is also a common laboratory method for preparing the gas. Equivalently, it can be obtained by heating a mixture of sodium nitrate and ammonium sulfate: [53] 2 NaNO 3 + (NH 4) 2 SO 4 → Na 2 SO 4 + 2 N 2 O + 4 H 2 O. Another method involves the reaction of urea, nitric acid and sulfuric acid: [54]