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The symptoms and the treatment of an overdose are generally the same as for the other tricyclic antidepressants, including anticholinergic effects, serotonin syndrome and adverse cardiac effects. TCAs, particularly nortriptyline, have a relatively narrow therapeutic index, which increase the chance of an overdose (both accidental and intentional).
Dextromethorphan/quinidine is a combination of these two generic drugs, and is the first FDA-approved drug for the treatment of PBA, approved on October 29, 2010. [ 50 ] In the pivotal multicenter study that led to its approval, the "Objectives...[were] to evaluate the safety, tolerability, and efficacy of two different doses of AVP-923 ...
A concussion, also known as a mild traumatic brain injury (mTBI), is a head injury that temporarily affects brain functioning. [8] Symptoms may include headache, dizziness, difficulty with thinking and concentration, sleep disturbances, mood changes, a brief period of memory loss, brief loss of consciousness; problems with balance; nausea; blurred vision; and mood changes.
A medical assessment by a physician or nurse practitioner is required if a concussion is suspected in an infant, child, or adolescent to rule out a more serious head injury and diagnose the concussion. [6] Treatment for concussion includes a short cognitive and physical period of rest followed by gradual return to activity and school.
The researchers found that while nortriptyline was associated with moderate weight gain over a period of six months, the people who were treated with escitalopram only gained 0.14kg (under a third ...
Initial treatment of an acute overdose includes gastric decontamination. This is achieved by giving activated charcoal, which adsorbs the drug in the gastrointestinal tract either by mouth or via a nasogastric tube. Activated charcoal is most useful if given within 1 to 2 hours of ingestion. [10]
Concussion, a type of mild traumatic brain injury that is caused by a direct or indirect hit to the head, body, or face is a common injury associated with sports and can affect people of all ages. A concussion is defined as a "complex pathophysiological process affecting the brain, induced by biomechanical forces". [1]
Post-concussion syndrome (PCS), also known as persisting symptoms after concussion, is a set of symptoms that may continue for weeks, months, or years after a concussion. PCS is medically classified as a mild traumatic brain injury (TBI).