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Ocular hypertension is the presence of elevated fluid pressure inside the eye (intraocular pressure), usually with no optic nerve damage or visual field loss. [1] [2]For most individuals, the normal range of intraocular pressure is between 10 mmHg and 21 mmHg. [3]
Intraocular pressure varies throughout the night and day. The diurnal variation for normal eyes is between 3 and 6 mmHg and the variation may increase in glaucomatous eyes. During the night, intraocular pressure may not decrease [17] despite the slower production of aqueous humour. [18]
Hypotony may occur either due to decreased production of aqueous humor or due to increased outflow. Hypotony has many causes including post-surgical wound leak from the eye, chronic inflammation within the eye including iridocyclitis, hypoperfusion, tractional ciliary body detachment or retinal detachment. [5]
The internal wall of the canal is very delicate and allows the fluid to filter due to the high pressure of the fluid within the eye. [7] The secondary route is the uveoscleral drainage , and is independent of the intraocular pressure, the aqueous flows through here, but to a lesser extent than through the trabecular meshwork (approx. 10% of the ...
For eye pressures, a value of 28 hPa (21 mmHg) above atmospheric pressure 1,010 hPa (760 mmHg) is often used, with higher pressures leading to a greater risk. [2] [26] However, some may have high eye pressure for years and never develop damage. [2] Conversely, optic nerve damage may occur with normal pressure, known as normal-tension glaucoma. [27]
[2] [26] Pulmonary artery pressure increases in an effort to oxygenate more blood. Full hematological adaptation to high altitude is achieved when the increase of red blood cells reaches a plateau and stops. The length of full hematological adaptation can be approximated by multiplying the altitude in kilometres by 11.4 days.