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Heterochromia is a variation in coloration most often used to describe color differences of the iris, but can also be applied to color variation of hair [1] or skin. Heterochromia is determined by the production, delivery, and concentration of melanin (a pigment ).
A rare predominantly black cat with odd eyes. The odd-eyed colouring is caused when either the epistatic (recessive) white gene or dominant white (which masks any other colour genes and turns a cat completely solid white) [3] or the white spotting gene (which is the gene responsible for bicolour coats) [4] prevents melanin granules from reaching one eye during development, resulting in a cat ...
Occasionally, heterochromia can be a sign of a serious medical condition. A common cause in females with heterochromia is X-inactivation, which can result in a number of heterochromatic traits, such as calico cats. Trauma and certain medications, such as some prostaglandin analogues, can also cause increased pigmentation in one eye. [88]
Woman with Waardenburg syndrome type 2, showing heterochromia and white forelock. The difference that defines type 2 from type 1 is that patients do not have the wider gap between the inner corners of the eyes (telecanthus/dystopia canthorum). Sensorineural hearing loss tends to be more common and more severe in this type.
Heterochromia iridum; Leucism, a partial loss of pigmentation that results in animals with pale or white skin, hair and/or feathers; Melanosis, hyperpigmentation via increased melanin Ocular melanosis; Peutz–Jeghers syndrome, dark patches on the lips etc. Piebaldism, patchy absence of melanin-producing cells
A completely deaf, solid white, blue-eyed cat A deaf white cat with yellow eyes. This engraving depicts two cats on a wall with a dog barking below them. The spotted cat hisses at the dog while the deaf white cat dozes, unaware of the barking.
Albinism is a congenital condition characterized in humans by the partial or complete absence of pigment in the skin, hair and eyes. Albinism is associated with a number of vision defects, such as photophobia, nystagmus, and amblyopia.
Fuchs heterochromic iridocyclitis (FHI) is a chronic unilateral uveitis appearing with the triad of heterochromia, predisposition to cataract and glaucoma, and keratitic precipitates on the posterior corneal surface. Patients are often asymptomatic and the disease is often discovered through investigation of the cause of the heterochromia or ...