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Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds. [1] [2] As of 2024, there are eight recognized genera. [3]Fourteen species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent.
A map of the murine polyomavirus genome, indicating the early genes (LTag, MTag, and STag) at right in blue and the late genes (the viral capsid proteins) at left in red. . Each region is transcribed as a single messenger RNA and alternatively spliced to express multiple proteins; the exons are shown as thickened lin
Mammals and birds serve as natural hosts. There are currently 13 species in this family, divided among 1 genera, Polyomavirus (type species Simian virus 40 ). Diseases associated with this family include: JCPyV: progressive multifocal leukoencephalopathy; BKPyV: mild respiratory infection.
Murine polyomavirus (also known as mouse polyomavirus, Polyomavirus muris, or Mus musculus polyomavirus 1, and in older literature as SE polyoma or parotid tumor virus; abbreviated MPyV) is an unenveloped double-stranded DNA virus of the polyomavirus family. The first member of the family discovered, it was originally identified by accident in ...
The BK virus, also known as Human polyomavirus 1, is a member of the polyomavirus family. Past infection with the BK virus is widespread, [1] but significant consequences of infection are uncommon, with the exception of the immunocompromised and the immunosuppressed. BK virus is an abbreviation of the name of the first patient, from whom the ...
The bird flu virus strain that is rampant among dairy cows in the U.S. may only need one mutation for it to be able to spread among humans, according to a study published this week.
In raw milk samples spiked with high amounts of bird flu virus, small amounts of infectious virus were still detectable after treatment with a standard pasteurization method, researchers said on ...
Murine polyomavirus (MPyV), described in the 1950s, was the first polyomavirus discovered and can cause tumors in rodents. MPyV has three early proteins; in addition to LTag and STag it also expresses middle tumor antigen , which is primarily responsible for the virus's transforming activity.