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The most common side effects of metformin include: Diarrhea. Nausea. Vomiting. ... Metformin overdose can include the following symptoms: ... Taking metformin may cause unpleasant side effects ...
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [ 76 ] [ 81 ] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
The medication most commonly may cause stomach upset and symptoms such as diarrhea but in general is well tolerated and has a relatively low chance of causing hypoglycemia. [35] One rare (about 1% chance) but serious side affect of metformin is that it can cause lactic acidosis, usually in patients with poor kidney function. [35]
Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. Does Metformin Cause Diarrhea?
Diarrhea. Flatulence. Asthenia (feeling weak or lacking energy) Stomach pain. Headache. Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication ...
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...
Metformin should not be used in those with severe kidney or liver problems. [24] The American Diabetes Association and European Association for the Study of Diabetes recommend using a GLP-1 receptor agonist or SGLT2 inhibitor as the first-line treatment in patients who have or are at high risk for atherosclerotic cardiovascular disease , heart ...
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.