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No definitive cause of endometrial polyps is known, but they appear to be affected by hormone levels and grow in response to circulating estrogen. [3] Risk factors include obesity, high blood pressure and a history of cervical polyps. [3] Taking tamoxifen or hormone replacement therapy can also increase the risk of uterine polyps.
During implantation, the embryo must cross the epithelial layer of the maternal endometrium before invading and implanting in the stroma layer. Maternal factors, including congenital uterine abnormalities, fibroids, endometrial polyps, intrauterine adhesions, adenomyosis, thrombophilia and endometriosis, can reduce the chances of implantation and result in RIF.
Endometrial intraepithelial neoplasia (EIN) is a premalignant lesion of the uterine lining that predisposes to endometrioid endometrial adenocarcinoma. It is composed of a collection of abnormal endometrial cells, arising from the glands that line the uterus , which have a tendency over time to progress to the most common form of uterine cancer ...
Specifically, obesity, type II diabetes, and insulin resistance are risk factors for Type I endometrial cancer. [21] Obesity increases the risk for endometrial cancer by 300–400%. [22] Estrogen replacement therapy during menopause when not balanced (or "opposed") with progestin is another risk factor.
Dr. Pedro Ramirez, MD, FACOG, the Chair of the Department of Obstetrics and Gynecology at Houston Methodist and a gynecologic oncologist, says that one of the biggest risk factors of endometrial ...
Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus. Most cases of endometrial hyperplasia result from high levels of estrogens , combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this ...
uterine disease [13] chlamydia or other sexually transmitted infection [12] [14] [15] atrophic vaginitis [12] childbirth; inadequate vaginal lubrication [4] benign polyps; cervical erosion (inflammation of the cervix) [12] [4] cervical or vaginal cancer [12] anatomical abnormality of the uterus, vagina or both. [13] pregnancy; endometrial ...
Nonhormonal treatments: For people who aren't interested in taking hormones or who can't — for instance, breast cancer patients whose treatments and risk factors preclude hormone therapy ...