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Phosphoribosyl pyrophosphate (PRPP) is a pentose phosphate. It is a biochemical intermediate in the formation of purine nucleotides via inosine-5-monophosphate , as well as in pyrimidine nucleotide formation.
The product of this reaction, phosphoribosyl pyrophosphate (PRPP), is used in numerous biosynthesis (de novo and salvage) pathways. PRPP provides the ribose sugar in de novo synthesis of purines and pyrimidines, used in the nucleotide bases that form RNA and DNA. PRPP reacts with orotate to form orotidylate, which can be converted to uridylate (UMP
R5P converts to PRPP, which forces an overproduction of purines, leading to uric acid build up. [8] Accumulation of PRPP is found in Lesch-Nyhan Syndrome. [16] The build up is caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT), which leads to decreased nucleotide synthesis and an increase of uric acid ...
Image credits: ambitioushandling "Various treats are a great way to make a cat sit quietly for some time, enough to take a couple of good shots," says Ivan Strahov, a photographer from Ukraine ...
Feline cutaneous asthenia is a rare inheritable skin disease of cats characterised by abnormal elasticity, stretching, and improper healing of the skin. Pendulous wing-like folds of skin form on the cat's back, shoulders and haunches. Even stroking the cat can cause the skin to stretch and tear.
Because every photo features all of the cuteness of one cat multiplied by three, four or even more! We took a trip to the Council of Cats subreddit and gathered some of their most adorable pics below.
Since we know that cats not eating become dehydrated, the same thing happens to the immune system with them. A cat that is already dealing with an infection will just get worse. 4. Depression
The hair of a cat is made of mainly protein, and cats need about 25-30% protein in their diets, much higher than what a dog needs. [5] A deficiency in protein usually happens when kittens are fed dog food or when low-protein diets are fed improperly. [5] If a cat has a protein deficiency, the cat will lose weight.