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Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Other members of the same genus include yellow fever virus, West Nile virus, and Zika virus. Dengue virus genome (genetic material) contains about 11,000 nucleotide bases, which code for the three structural protein molecules (C, prM and E) that form the virus particle and seven other protein molecules that are required for replication of the ...
The recent spread of Dengue can also be attributed to rapid population growth, increased coagulation in urban areas, and global travel. Without sufficient vector control, the dengue virus has evolved rapidly over time, posing challenges to both government and public health officials. [58] Malaria is caused by a protozoan called Plasmodium ...
In a small proportion of cases, the disease develops into the life-threatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. [2] Dengue is spread by several species of mosquito of the Aedes type, principally A ...
65,758 cases of dengue fever have been reported up to EW 19 in Mexico, accounting for 0.8% of total cases in Latin America and the Caribbean in 2024. 405 severe cases and 20 deaths have been reported so far in Mexico, with a fatality rate of 0.03%.
Epidemic dengue has become more common since the 1980s. By the late 1990s, dengue was the most important mosquito-borne disease affecting humans after malaria, with around 40 million cases of dengue fever and several hundred thousand cases of dengue hemorrhagic fever each year. Significant outbreaks of dengue fever tend to occur every five or ...
Dengue fever (UK: / ˈ d ɛ ŋ ɡ eɪ / or US: / ˈ d ɛ ŋ ɡ iː /), also known as breakbone fever, is an infectious tropical disease caused by the dengue virus.Symptoms include fever, headache, myalgias and arthralgias, and a characteristic skin rash that is similar to measles.
Dengue is a Flaviviridae virus, with five genetic types. [ 8 ] [ 9 ] Here is the virus drawn as a 3-dimensional model of the envelope protein. [ 10 ] Dengue is in the same family as other well known viruses carried by mosquitoes that cause tropical diseases, such as yellow fever , West Nile , and Zika virus .