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Shortly afterward, physicians began discussing anesthesia to reduce pain during rapid detox. Norbert Loimer, MD, Ph.D. published a paper in the '80s outlining the success of opiate detoxification under general anesthesia. Resnick and Loimer's early research served as the foundation for all forms of detoxification under sedation procedures used ...
From 1993, Waismann started to treat opiate addiction using a relatively new technique named Ultra Rapid Opiate Detoxification (UROD). [19] [20] This method was used until 1997, when Waismann redefined this treatment method and renamed it ANR - Accelerated Neuro-Regulation. The principle on which the ANR therapy is based is the acceleration of ...
Opioid withdrawal is a set of symptoms (a syndrome) ... Opioid use triggers a rapid adaptation in cellular signaling pathways that, when reduced or stopped, can cause ...
Laura Duke, who was recently the detox unit’s supervisor, said the cost put the medication out of reach for all but 1 to 2 percent of the addicts she saw. Detoxing is a first step towards sobriety. To overcome the inevitable pain of withdrawal from opiates without medication—going “cold turkey”—is excruciating.
All available studies collected in the 2005 Australian National Evaluation of Pharmacotherapies for Opioid Dependence suggest that maintenance treatment is preferable, [22] with very high rates (79–100%) [22] of relapse within three months of detoxification from levo-α-acetylmethadol , buprenorphine, and methadone. [22] [23]
Vertex began researching the drug in the 2000s when overdoses were rocketing upward, principally driven by mass prescribing of opioid painkillers for common ailments like arthritis and back pain.
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