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LSD, a classical psychedelic, is deemed physiologically safe at standard dosages (50–200 μg) and its primary risks lie in psychological effects rather than physiological harm. [ 24 ] [ 59 ] A 2010 study by David Nutt ranked LSD as significantly less harmful than alcohol , placing it near the bottom of a list assessing the harm of 20 drugs.
Bill Wilson, the founder of Alcoholics Anonymous, used LSD during supervised experiments with Betty Eisner, Gerald Heard, and Aldous Huxley. He ingested LSD for the first time on August 29, 1956. With Wilson's invitation, his wife Lois, his spiritual adviser Father Ed Dowling, and Nell Wing also participated in experimentation of this drug.
1D-LSD (1-(1,2-dimethylcyclobutane-1-carbonyl)-lysergic acid diethylamide, SYN-L-229) is a psychotropic substance and a research chemical that has potential psychedelic effects. It is believed to be a prodrug for LSD and has replaced 1V-LSD in Germany after 1V-LSD became covered by the German NpSG law in 2022. [ 1 ]
Research has been conducted, however, and studies show that psychedelics are physiologically safe and rarely lead to addiction. [ 18 ] [ 19 ] Studies conducted using psilocybin in a psychotherapeutic setting reveal that psychedelic drugs may assist with treating depression , alcohol addiction , and nicotine addiction .
NBOMe and NBOHs are regularly sold as LSD in blotter papers, [25] [33] which have a bitter taste and different safety profiles. [27] [24] Despite high potency, recreational doses of LSD have only produced low incidents of acute toxicity. [24]
The LSD is taken first, followed by the MDMA 4 hours later and then 2C-B is taken 2 hours after the MDMA ( so 6 hours after the LSD ). MDMA can be replaced by 6-APB , 5-APB , 6-MAPB or 5-MAPB , in this case the Empathogen is taken 2 hours after the LSD, while 2C-B may be replaced by 2C-C , 2C-D or 2C-B-FLY .
The interview has since gained traction on social media. Luckily, Cooper did his due diligence where LSD is concerned, reminding viewers, “We don’t recommend this at home.” ...
[21] [22] [23] There currently is a bill pending in the California State Legislature that would legalize the "possession, obtaining, giving away, or transportation of, specified quantities of psilocybin, psilocyn, dimethyltryptamine (DMT), ibogaine, mescaline, lysergic acid diethylamide (LSD), and 3,4-methylenedioxymethamphetamine (MDMA)."