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In a 2011 study, half of the HLA alleles of modern Eurasians were shown to represent archaic HLA haplotypes, and were inferred to be of Denisovan or Neanderthal origin. [70] A haplotype of EPAS1 in modern Tibetans, which allows them to live at high elevations in a low-oxygen environment, likely came from Denisovans.
It has been observed that Denisovans contributed genes to Melanesians but not to East Asians, indicating that there was interaction between the early ancestors of Melanesians with Denisovans but that this interaction did not take place in the regions near southern Siberia, where as-of-yet the only Denisovan remains have been found. [72]
Denisovan ancestry is shared by Melanesians, Aboriginal Australians, and smaller scattered groups of people in Southeast Asia, such as the Mamanwa, a Negrito people in the Philippines, suggesting the interbreeding took place in Eastern Asia where the Denisovans lived.
Denisovans survived and thrived on the high-altitude Tibetan plateau for more than 100,000 years, according to a new study that deepens scientific understanding of the enigmatic ancient humans ...
The Neanderthal DNA found in modern human genomes has long raised questions about ancient interbreeding. New studies offer a timeline of when that occurred and when ancient humans left Africa.
[96] [99] Evidence has also been found that as much as 6% of the DNA of some modern Melanesians derive from Denisovans, indicating limited interbreeding in Southeast Asia. [100] [101] Alleles thought to have originated in Neanderthals and Denisovans have been identified at several genetic loci in the genomes of modern humans outside Africa.
Researchers first identified Denisovans in 2010 using DNA sequences extracted from a rare tiny fragment of finger bone found in Siberia. Now, Baishiya Karst Cave, on the northeastern edge of the ...
The time of divergence between archaic H. sapiens and ancestors of Neanderthals and Denisovans caused by a genetic bottleneck of the latter was dated at 744,000 years ago, combined with repeated early admixture events and Denisovans diverging from Neanderthals 300 generations after their split from H. sapiens, as calculated by Rogers et al. (2017).