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In other words, as many as 4 million people in the U.S. who currently take statins for primary prevention — meaning they have not had a cardiovascular event such as a stroke or heart attack ...
The exact mechanism responsible for the possible increased risk of diabetes mellitus associated with statin use is unclear. [105] However, recent findings have indicated the inhibition of HMGCoAR as a key mechanism. [109] Statins are thought to decrease cells' uptake of glucose from the bloodstream in response to the hormone insulin. [105]
These guidelines recommend statin therapy for adults between forty and seventy-five who have diabetes, high cholesterol levels, or an estimated 10-year atherosclerotic cardiovascular disease risk ...
A new analysis re-evaluates statins and who should use them. Statins are widely used to help lower cholesterol. Using a new analysis, researchers found that millions of people may be taking ...
Once lipid-lowering therapy is initiated, people with type 2 diabetes mellitus should be taking at least moderate doses of a statin. [84] For those people with type 2 diabetes who are taking statins, routine monitoring of liver function tests or muscle enzymes is not recommended except in specific circumstances.
Aluminum and magnesium hydroxide antacids should not be taken within two hours of taking rosuvastatin [4] Coadministration of rosuvastatin with eluxadoline may increase the risk of rhabdomyolysis and myopathy [24] Grapefruit juice negatively interacts with several specific drugs in the statin class, but it has little or no effect on ...