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  2. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors.

  3. Category:SGLT2 inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:SGLT2_inhibitors

    Pages in category "SGLT2 inhibitors" The following 27 pages are in this category, out of 27 total. This list may not reflect recent changes. ...

  4. Discovery and development of gliflozins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Because sodium is absorbed at the same time as glucose via SGLT-2, the upregulation of SGLT-2 probably leads to development or maintenance of hypertension. In study where rats were given either ramipril or losartan, levels of SGLT-2 protein and mRNA were significantly reduced. In patients with diabetes, hypertension is a common problem so this ...

  5. A diabetes drug may help prevent dementia, new research shows

    www.aol.com/diabetes-drug-may-help-prevent...

    SGLT-2 inhibitors are relatively new drugs that treat type 2 diabetes. The first SGLT-2 inhibitor approved for use in the United States was dapagliflozin (Farxiga) , in 2014.

  6. A Common Drug Could Lower Your Dementia Risk By 35 ... - AOL

    www.aol.com/common-drug-could-lower-dementia...

    People who took SGLT-2 inhibitors for longer periods of time seemed to have the best results. “SGLT-2 inhibitors might prevent dementia, providing greater benefits with longer treatment,” the ...

  7. Top aging expert says these 4 FDA-approved drugs hold promise ...

    www.aol.com/finance/global-aging-doctor-says-4...

    SGLT2 inhibitors, blood-sugar-lowering drugs, are the only drugs on the list scoring a perfect score on Barzilai’s scale. The inhibitors are typically prescribed for those with type 2 diabetes ...

  8. Sodium-glucose transport proteins - Wikipedia

    en.wikipedia.org/wiki/Sodium-glucose_transport...

    SGLT2 inhibitors, also called gliflozins, [14] are used in the treatment of type 2 diabetes. SGLT2 is only found in kidney tubules and in conjunction with SGLT1 resorbs glucose into the blood from the forming urine. By inhibiting SGLT2, and not targeting SGLT1, glucose is excreted which in turn lowers blood glucose levels.

  9. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment