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End organ damage is severe impairment of major body organs due to systemic disease. Commonly this is referred to in diabetes , high blood pressure , or states of low blood pressure or low blood volume. [ 1 ]
Neuromuscular junction (motor end-organ) Lamellar corpuscle (Pacinian corpuscle end-organ) The ultimately affected organ in a chain of events, such as a disease process (pathophysiology) or a drug's mechanism of action (sometimes called a target organ in this sense) End organ damage, disease of such organs Ambulatory blood pressure § Target ...
Kidney failure, also known as renal failure or end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. [2]
People with MGUS have a monoclonal gammopathy (presence of monoclonal immunoglobulins) but does not meet the criteria for the clonal burden nor the presence of end organ damage seen in hematologic malignancies. In a population based study based on the NHANES III health survey; 6% of patients with MGUS were subsequently classified as having MGRS ...
Septic shock is a potentially fatal medical condition that occurs when sepsis, which is organ injury or damage in response to infection, leads to dangerously low blood pressure and abnormalities in cellular metabolism. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defines septic shock as a subset of sepsis ...
This hemodynamic collapse results in poor blood flow to the brain and other organs, which if prolonged causes persistent damage. There are many different types of arrhythmias, but the ones most frequently recorded in sudden cardiac arrest are ventricular tachycardia and ventricular fibrillation .
Causes of gastrointestinal bleeding. Gastrointestinal bleeding can be roughly divided into two clinical syndromes: upper gastrointestinal bleeding and lower gastrointestinal bleeding. [2]
Oxidative damage may occur in any cell in the body but the effects on the three most susceptible organs will be the primary concern. It may also be implicated in damage to red blood cells , [7] [8] the liver, [9] heart, [10] endocrine glands (adrenal glands, gonads, and thyroid), [11] [12] [13] or kidneys, [14] and general damage to cells. [2] [15]