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  2. Phase response curve - Wikipedia

    en.wikipedia.org/wiki/Phase_response_curve

    Each curve has one peak and one trough in each 24-hour cycle. Relative circadian time is plotted against phase-shift magnitude. The treatment is usually narrowly specified as a set intensity and colour and duration of light exposure to the retina and skin, or a set dose and formulation of melatonin.

  3. Circadian rhythm - Wikipedia

    en.wikipedia.org/wiki/Circadian_rhythm

    A circadian rhythm (/ s ər ˈ k eɪ d i ə n /), or circadian cycle, is a natural oscillation that repeats roughly every 24 hours.Circadian rhythms can refer to any process that originates within an organism (i.e., endogenous) and responds to the environment (is entrained by the environment).

  4. Light effects on circadian rhythm - Wikipedia

    en.wikipedia.org/wiki/Light_effects_on_circadian...

    In response to light exposure, alertness levels can increase as a result of suppression of melatonin secretion. [3] [6] A linear relationship has been found between alerting effects of light and activation in the posterior hypothalamus. [3] [24] Disruption of circadian rhythm as a result of light also produces changes in metabolism. [4]

  5. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  6. Doctors Say This Viral "Sleep Rule" Actually Works - AOL

    www.aol.com/doctors-viral-sleep-rule-actually...

    10 hours before bed: No more caffeine ... “There’s a lot of data that says the light disrupts the circadian rhythm and delays sleep onset,” says Dr. Sunderram. “It also inhibits melatonin ...

  7. Chronodisruption - Wikipedia

    en.wikipedia.org/wiki/Chronodisruption

    The human body is synchronized to a 24-hour light-dark cycle, which is essential for maintaining optimal health and well-being. However, modern lifestyles —which involve exposure to artificial light (especially during nighttime), irregular sleep schedules, and shift work — can disrupt this natural rhythm, leading to a range of adverse ...