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An axo-axonic synapse is a type of synapse, formed by one neuron projecting its axon terminals onto another neuron's axon. [1] Axo-axonic synapses have been found and described more recently than the other more familiar types of synapses, such as axo-dendritic synapses and axo-somatic synapses.
Presynaptic inhibition is a phenomenon in which an inhibitory neuron provides synaptic input to the axon of another neuron (axo-axonal synapse) to make it less likely to fire an action potential. Presynaptic inhibition occurs when an inhibitory neurotransmitter, like GABA, acts on GABA receptors on the axon terminal.
It is believed that they provide inhibitory input to the pyramidal neurons, but there is data showing that in some circumstances the GABA from chandelier neurons could be excitatory. [ 7 ] The axon cartridges formed by chandelier cells are one of the synapse types that show the most dramatic changes during normal adolescence, [ 8 ] and could ...
Diagram of a chemical synaptic connection. In the nervous system, a synapse [1] is a structure that allows a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or a target effector cell.
Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain ), and recent studies have supported the existence of permissively gated synaptic transmission.
Axon terminals (also called terminal boutons, synaptic boutons, end-feet, or presynaptic terminals) are distal terminations of the branches of an axon. An axon, also called a nerve fiber, is a long, slender projection of a nerve cell that conducts electrical impulses called action potentials away from the neuron's cell body to transmit those ...
Nationality: Spanish: Education: University of Zaragoza: Known for: Fathering modern neuroscience Discovery of the neuron Cajal body, Cajal–Retzius cell, Interstitial cell of Cajal, Neuron doctrine, Growth cone, Dendritic spine, Long-term potentiation, Mossy fiber, Neurotrophic theory, Axo-axonic synapse, Pioneer axon, Pyramidal cell, Radial glial cell, Retinal ganglion cell, Trisynaptic ...
Later, synaptic vesicles could also be isolated from other tissues such as the superior cervical ganglion, [40] or the octopus brain. [41] The isolation of highly purified fractions of cholinergic synaptic vesicles from the ray Torpedo electric organ [42] [43] was an important step forward in the study of vesicle biochemistry and function.