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  2. Discovery and development of beta-blockers - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The progress in β-blocker development led to the introduction of drugs with variety of properties. β-blockers were developed having a relative selectivity for cardiac β1-receptors (for example metoprolol and atenolol), partial adrenergic agonist activity , concomitant α-adrenergic blocking activity (for example labetalol and carvedilol) and ...

  3. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina, high blood pressure and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]

  4. Carvedilol - Wikipedia

    en.wikipedia.org/wiki/Carvedilol

    Carvedilol is a nonselective beta blocker and alpha-1 blocker. [5] How it improves outcomes is not entirely clear but may involve dilation of blood vessels. [5] Carvedilol was patented in 1978 and approved for medical use in the United States in 1995. [5] [8] It is on the World Health Organization's List of Essential Medicines. [9]

  5. Beta blocker - Wikipedia

    en.wikipedia.org/wiki/Beta_blocker

    [14] [15] [16] Bisoprolol, carvedilol, and sustained-release metoprolol are specifically indicated as adjuncts to standard ACE inhibitor and diuretic therapy in congestive heart failure, although at doses typically much lower than those indicated for other conditions. Beta blockers are only indicated in cases of compensated, stable congestive ...

  6. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    Another treatment for hypertension is using drugs that have both α 1 blocking activity, as well as nonselective β activity, such as Labetalol or carvedilol. [19] In low doses, labetalol and carvedilol can decrease the peripheral resistance and block the effects of isoprenaline to reduce hypertensive symptoms. [19]

  7. Outpatient surgery - Wikipedia

    en.wikipedia.org/wiki/Outpatient_surgery

    Outpatient surgery, also known as ambulatory surgery, day surgery, [1] day case surgery, or same-day surgery, is surgery that does not require an overnight hospital stay. [ note 1 ] The term “ outpatient ” arises from the fact that surgery patients may enter and leave the facility on the same day.

  8. Inotrope - Wikipedia

    en.wikipedia.org/wiki/Inotrope

    While negative inotropism may precipitate or exacerbate heart failure in the short term, certain beta blockers (e.g. carvedilol, bisoprolol and metoprolol) have been believed to reduce long-term morbidity and mortality in congestive heart failure. [13] Examples of negative inotropic agents include: Beta blockers [14]

  9. Nadolol - Wikipedia

    en.wikipedia.org/wiki/Nadolol

    Four of the stereoisomers of nadolol. Nadolol is a non-selective beta blocker; that is, it non-selectively blocks both beta-1 and beta-2 receptors.It has a preference for beta-1 receptors, which are predominantly located in the heart, thereby inhibiting the effects of catecholamines and causing a decrease in heart rate and blood pressure.