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CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
The trigeminal nerve.. ATN is usually attributed to inflammation or demyelination, with increased sensitivity of the trigeminal nerve.These effects are believed to be caused by infection, demyelinating diseases, or compression of the trigeminal nerve (by an impinging vein or artery, a tumor, dental trauma, accidents, or arteriovenous malformation) and are often confused with dental problems.
This disorder is characterized by episodes of severe facial pain along the trigeminal nerve divisions. The trigeminal nerve is a paired cranial nerve that has three major branches: the ophthalmic nerve (V 1), the maxillary nerve (V 2), and the mandibular nerve (V 3). One, two, or all three branches of the nerve may be affected.
PNS recurrence is rarely resectable, and repeated irradiation has greater toxic side effects and fewer benefits compared with initial early treatment. The trigeminal nerve and facial nerve are the most commonly affected nerves primarily because of their extensive innervation area, although virtually any cranial nerve and its branches can ...
Tumour of facial nerve like schwannomas and perineuromas. Other tumours that can compress facial nerve along its course like congenital cholesteatomas, hemangiomas, acoustic neuromas, parotid gland neoplasms, or metastases of other tumors. Other causes like viral, bacterial or fungal infections like chicken pox, streptococcal infection or ...
Cell morphology observed in all nerve root schwannomas. Trigeminal schwannoma is a condition in which a tumor forms on the trigeminal nerve (also known as cranial nerve five). [1] This prevents sensation in the area associated with the nerve. In the case of the trigeminal nerve, this is the face, meaning hypoesthesia of the face is experienced.
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