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Memantine, sold under the brand name Namenda among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. [10] [11] [8] It is taken by mouth. [10] [8] Common side effects include headache, constipation, sleepiness, and dizziness. [10] [11] Severe side effects may include blood clots, psychosis, and heart ...
Memantine (Namenda) - treats Dementia and Alzheimer's. N. Neurontin – an anticonvulsant which is sometimes used as a mood stabilizer, anti-anxiety agent or to ...
Memantine/donepezil, sold under the brand name Namzaric among others, is a fixed dose combination medication used for the treatment of dementia of the Alzheimer's type. [1] It contains memantine , as the hydrochloride, a NMDA receptor antagonist ; and donepezil as the hydrochloride, an acetylcholinesterase inhibitor . [ 1 ]
Memantine (Namenda) for OCD: memantine is approved for the treatment of Alzheimer's disease. Methotrexate (MTX), approved for the treatment of choriocarcinoma, is frequently used for the medical treatment of an unruptured ectopic pregnancy. [14]
Like memantine, nitromemantine is a low-affinity voltage-dependent uncompetitive antagonist at glutamatergic NMDA receptors, however nitromemantine selectively inhibits extrasynaptic NMDA receptors while sparing normal physiological synaptic NMDA receptor activity, resulting in less side effects and a greater neuroprotective action, as well as stimulating regrowth of synapses with prolonged ...
Reported adverse events with memantine are infrequent and mild, including hallucinations, confusion, dizziness, headache and fatigue. [ 196 ] [ 197 ] The combination of memantine and donepezil [ 198 ] has been shown to be "of statistically significant but clinically marginal effectiveness".
Neramexane is a drug related to memantine, [1] which acts as an NMDA antagonist [2] and has neuroprotective effects. [3] It is being developed for various possible applications, including treatment of tinnitus, [4] [5] Alzheimer's disease, [6] drug addiction [7] and as an analgesic. [8]
Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.