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Irbesartan, sold under the brand name Aprovel among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [5] It is a reasonable initial treatment for high blood pressure. [5] It is taken by mouth. [5] Versions are available as the combination irbesartan/hydrochlorothiazide. [5] [6] [7] [8]
Common side effects of valproate include nausea, vomiting, somnolence, and dry mouth. [7] Serious side effects can include liver failure, and regular monitoring of liver function tests is therefore recommended. [7] Other serious risks include pancreatitis and an increased suicide risk. [7]
Angiotensin II, through AT 1 receptor stimulation, is a major stress hormone and, because (ARBs) block these receptors, in addition to their eliciting anti-hypertensive effects, may be considered for the treatment of stress-related disorders. [15] In 2008, they were reported to have a remarkable negative association with Alzheimer's disease (AD).
Common side effects include headache, low blood pressure, nausea, and constipation. [9] Other side effects include allergic reactions and muscle pains. [12] It is not recommended in people with a slow heart rate or heart failure. [12] It is believed to cause problems for the fetus if used during pregnancy. [2]
A liver support system or diachysis is a type of therapeutic device to assist in performing the functions of the liver. Such systems focus either on removing the accumulating toxins (liver dialysis), or providing additional replacement of the metabolic functions of the liver through the inclusion of hepatocytes to the device (bioartificial liver device).
When the kidneys detect low blood pressure, the renin–angiotensin–aldosterone system (RAAS) is activated and eventually, aldosterone is secreted. Aldosterone binds to aldosterone receptors (mineralocorticoid receptors) increasing sodium reabsorption in an effort to increase blood pressure and improve fluid status in the body.
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