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The primary hormones involved in regulating translocation appear to be the melanocortins, melatonin, and melanin-concentrating hormone (MCH), that are produced mainly in the pituitary, pineal gland, and hypothalamus, respectively. These hormones may also be generated in a paracrine fashion by cells in the skin.
The pseudopodial process (aka the tanning process) happens slowly in dermal melanocytes in response to ultraviolet light and to production of new melanosomes and increased donation of melanosomes to adjacent keratinocytes, which are typical skin surface cells. Donation occurs when some keratinocytes engulf the end of the melanocyte pseudopodia ...
The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a G protein–coupled receptor that binds to a class of pituitary peptide hormones known as the melanocortins, which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH).
These stem cells develop into both keratinocyte precursors and melanoblasts - and these melanoblasts supply both hair and skin (moving into the basal layer of the epidermis). There is additionally evidence that melanocyte stem cells are present in cutaneous nerves, with nerve signals causing these cells to differentiate into melanocytes for the ...
Close-up of fish melanophores. Fish coloration is produced through specialized cells called chromatophores. The dermal chromatophore is a basic color unit in amphibians, reptiles, and fish which has three cell layers: "the xanthophore (contains carotenoid and pteridine pigments), the iridophore (reflects color structurally), and the melanophore (contains melanin)". [5]
The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...
Corticotropes produce and release ACTH, a 39 amino acid peptide hormone, in response to corticotropic releasing hormone (CRH) release from the hypothalamus. CRH is a 41-amino-acid peptide hormone that is secreted by the parvocellular neurosecretory cells, which are found within the paraventricular nucleus of the hypothalamus. [9]
The porphyrin moieties in our red blood cells, whose primary function is to bind iron atoms which capture oxygen, result in the heme chromophores which give human blood its red color. Heme is degraded by the body into biliverdin (which gives bruises their blue-green color), which in turn is degraded into bilirubin (which gives patients with ...