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The cartoon of epithelium cells connected by tricellular junctions at the regions where three cells meet. Tricellular junctions are also implicated in the regulation of cytoskeletal organization and cell divisions. In particular they ensure that cells divide according to the Hertwig rule.
The cell then divides along the spindle apparatus orientation. The first insights into how cells could remember their long axis came from studies on the Drosophila epithelium. The study indicated the participation of tricellular junctions (TCJs) in determining the spindle orientation. TCJs localized at the regions where three or more cells meet.
Tight junctions also help maintain the apicobasal polarity of cells by preventing the lateral diffusion of integral membrane proteins between the apical and lateral/basal surfaces, allowing the specialized functions of each surface (for example receptor-mediated endocytosis at the apical surface and exocytosis at the basolateral surface) to be ...
Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
Thereby tight junction conducts signaling molecules, that influence the differentiation, proliferation and polarity of cells. So tight junction plays a key role in maintenance of osmotic balance and trans-cellular transport of tissue specific molecules. Nowadays is known more than 40 different proteins, that are involved in these selective TJ ...
Adjacent epithelial cells are connected by adherens junctions on their lateral membranes. They are located just below tight junctions. Their function is to give shape and tension to cells and tissues and they are also the site of cell-cell signaling. Adherens junctions are made of cell adhesion molecules from the cadherin family. There are over ...
it is a simplified diagram to show the diferent forms of cell junction. Date: 6 June 2006: Source: the image i made myself convining the images i had already done on the subject (Adherens Junctions, tight junction Gap junction)together with this images i found on the net , and. Image made with Adobe Ilustrator.
The main trait of septate junctions structure is that cross-bridges or septa are in the ladder-like shape and cover the 15–20 nm intermembrane space of cell–cell contacts. Septate junctions are in a tight arrangement which is parallel to each other. [4] For the septate junctions, several components are related to the function or the ...