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IDET (Intradiscal Electrothermal Annuloplasty) [1] is a recently developed minimally invasive form of annuloplasty consisting of the insertion of a hollow needle into the affected disc. Through this needle, a heating wire is passed.
Disk biacuplasty is a medical procedure that applies heat to the annulus of disks that separate the vertebra of the back with the goal of ablating the neurons that generate pain sensations. [1]
For example, percutaneous intradiscal radiofrequency thermocoagulation (PIRFT) involves the placement of an electrode or catheter into the intervertebral disc and applying an alternating radiofrequency current.
Kevin Pauza is an American physiatrist and interventional spine specialist. He is the co-founder of the Texas Spine and Joint Hospital located in Tyler, Texas. [1] Pauza developed the Discseel procedure [2] for the treatment of spinal disorders known as the Pauza Disc Treatment, [3] which claims to repair re-grow discs without a spinal fusion.
Over 100 mutations have been reported to date in the opsin gene associated with RP since the Pro23His mutation in the intradiscal domain of the protein was first reported in 1990. These mutations are found throughout the opsin gene and are distributed along the three domains of the protein (the intradiscal, transmembrane, and cytoplasmic domains).
Condoliase (Hernicore) is a biopharmaceutical for the treatment of lumbar disc herniation.Clinical trials have shown its benefit in alleviation of lumbar disc herniation associated low back pain and disability, although some concerns have been suggested with regard to promotion of disc degeneration.
Chymopapain (EC 3.4.22.6, chymopapain A, chymopapain B, chymopapain S, brand name Chymodiactin) is a proteolytic enzyme isolated from the latex of papaya (Carica papaya).It is a cysteine protease which belongs to the papain-like protease (PLCP) group. [1]
Menno Emanuël Sluijter (born 31 July 1932, Haarlem) is an anaesthetist from the Netherlands.. Sluijter obtained his MD at the University of Amsterdam in 1957 and his PhD at the same institution in 1963 with the dissertation The treatment of carbon monoxide poisoning by administration of oxygen at high atmospheric pressure. [1]