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There is the total protein test or the serum protein electrophoresis which measures the level of each protein in a patient's blood. The serum protein electrophoresis test focuses more on the immune system and if it is working properly and it measures the levels of several types of globulins or proteins in the blood. [6]
Serum total protein, also known as total protein, is a clinical chemistry parameter representing the concentration of protein in serum. [1] Serum contains many proteins including serum albumin, a variety of globulins, and many others. While it is possible to analyze these proteins individually, total protein is a relatively quick and ...
Serum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins. [1] The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma , a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy ...
Researchers have discovered that proteins in the blood could be used to detect over 60 ... using a protein detection test for the condition would result in 80% of cases being detected, with a 10% ...
A macroglobulin is a plasma globulin of high molecular weight. [1] Elevated levels of macroglobulins ( macroglobulinemia ) may cause manifestations of excess blood viscosity (as is the case for IgM antibodies in Waldenström macroglobulinemia ) and/or precipitate within blood vessels when temperature drops (as in cryoglobulinaemia ).
Overall, α 2-macroglobulin is the largest major nonimmunoglobulin protein in human plasma. The amino acid sequence of α 2-macroglobulin has been shown to be 71% the same as that of the pregnancy zone protein (PZP; also known as pregnancy-associated α 2-glycoprotein). [10]
When a paraproteinemia is present in the blood, there will be a narrow band, or spike, in the serum protein electrophoresis because there will be an excess of production of one protein. [2] There are two large classes of blood proteins: albumin and globulin. They are generally equal in proportion, but albumin is much smaller than globulin, and ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...