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Daratumumab, sold under the brand name Darzalex among others, is an anti-cancer monoclonal antibody medication. It binds to CD38 , [ 7 ] which is overexpressed in multiple myeloma cells. [ 8 ]
cryopyrin-associated periodic syndrome, Yao's Syndrome, Adult Onset Still's Disease: Cantuzumab mertansine [42] mab: humanized: CanAg (a glycoform of MUC1) colorectal cancer etc. Cantuzumab ravtansine [42] mab: humanized: CanAg (a glycoform of MUC1) cancers Caplacizumab [44] Cablivi: sdAb: humanized: VWF: Y: thrombotic thrombocytopenic purpura ...
It was approved for use in the United States in May 2020. [2] [7] [8]Efficacy of daratumumab and hyaluronidase-fihji (monotherapy) was evaluated in the COLUMBA trial (NCT03277105), an open-label non-inferiority trial randomizing 263 participants to daratumumab and hyaluronidase-fihj and 259 to intravenous daratumumab (daratumumab IV). [2]
Around seven percent of U.S. adults can’t pay for prescription drugs they need, according to a 2021 Gallup poll. That’s an estimated 18 million people who say they had to go without at least ...
Treatment of adults with locally advanced, unresectable (stage III) non-small cell lung cancer (NSCLC) whose disease has not progressed during or following concurrent or sequential platinum-based chemoradiation therapy and whose tumors have EGFR exon 19 deletions or exon 21 L858R mutations, as detected by an FDA-approved test [2]
Older adults are prone to dehydration for many reasons. Learn how to identify the symptoms of dehydration in older adults based on how they look and feel. Symptoms of Dehydration in Adults Older ...
Isatuximab, sold under the brand name Sarclisa, is a monoclonal antibody (mAb) medication for the treatment of multiple myeloma. [6] [4]The most common side effects include neutropenia (low levels of neutrophils, a type of white blood cell), infusion reactions, pneumonia (infection of the lungs), upper respiratory tract infection (such as nose and throat infections), diarrhoea and bronchitis ...
Symptoms of PAH may include shortness of breath, fatigue, and swelling of the body (such as the ankles and legs). [9] In reported cases, people developed PAH after starting dasatinib, including after more than one year of treatment. [9] Information about the risk was added to the Warnings and Precautions section of the Sprycel drug label. [9]
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