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Preload in such cases is important for several reasons. First, a tightened bolt experiences only a small fraction of any external load that will be applied later, so that a fully tightened bolt can (depending on the exact application) sustain a much greater load than a loosely tightened bolt.
Biological engineering or bioengineering is the application of principles of biology and the tools of engineering to create usable, tangible, economically viable products. [1] Biological engineering employs knowledge and expertise from a number of pure and applied sciences, [2] such as mass and heat transfer, kinetics, biocatalysts ...
Since sarcomere length cannot be determined in the intact heart, other indices of preload such as ventricular end-diastolic volume or pressure are used. As an example, preload increases when venous return is increased. This is because the end-diastolic pressure and volume of the ventricle are increased, which stretches the sarcomeres.
The Frank–Starling law of the heart (also known as Starling's law and the Frank–Starling mechanism) represents the relationship between stroke volume and end diastolic volume. [1] The law states that the stroke volume of the heart increases in response to an increase in the volume of blood in the ventricles , before contraction (the end ...
Quizlet is a multi-national American company that provides tools for studying and learning. [1] Quizlet was founded in October 2005 by Andrew Sutherland, who at the time was a 15-year old student, [ 2 ] and released to the public in January 2007. [ 3 ]
In cardiac physiology, preload is the amount of sarcomere stretch experienced by cardiac muscle cells, called cardiomyocytes, at the end of ventricular filling during diastole. [1] Preload is directly related to ventricular filling. As the relaxed ventricle fills during diastole, the walls are stretched and the length of sarcomeres increases.
Engineering biology is the set of methods for designing, building, and testing engineered biological systems which have been used to manipulate information, construct materials, process chemicals, produce energy, provide food, and help maintain or enhance human health and environment. [1]
Embedment is a phenomenon in mechanical engineering in which the surfaces between mechanical members of a loaded joint embed. It can lead to failure by fatigue as described below, and is of particular concern when considering the design of critical fastener joints.