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Biotin is a coenzyme for five carboxylases in the human body (propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, pyruvate carboxylase, and 2 forms of acetyl-CoA carboxylase.) Therefore, biotin is essential for amino acid catabolism, gluconeogenesis, and fatty acid metabolism.
Biotinidase deficiency is an autosomal recessive metabolic disorder in which biotin is not released from proteins in the diet during digestion or from normal protein turnover in the cell. This situation results in biotin deficiency. Biotin is an important water-soluble nutrient that aids in the metabolism of fats, carbohydrates, and proteins.
High-dose biotin (300 mg/day = 10,000 times adequate intake) has been used in clinical trials for treatment of multiple sclerosis, a demyelinating autoimmune disease. [37] [38] The hypothesis is that biotin may promote remyelination of the myelin sheath of nerve cells, slowing or even reversing neurodegeneration. The proposed mechanisms are ...
Discover what this essential B vitamin can do for your body and whether you need more in your diet.
Biotin is an essential B vitamin that helps the body convert food into energy and supports skin and hair health. Add these 7 biotin-rich foods to your diet for benefits.
For those in search of growing strong, healthy nails and thick, full hair, can biotin supplements actually offer a solution to common beauty concerns?. Biotin deficiency is a relatively uncommon ...
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