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It is one of the preferred treatments for high blood pressure in pregnancy. [1] For other types of high blood pressure including very high blood pressure resulting in symptoms other medications are typically preferred. [1] It can be given by mouth or injection into a vein. [1] Onset of effects is around 5 hours and they last about a day. [1]
Central alpha agonists lower blood pressure by stimulating alpha-receptors in the brain which open peripheral arteries easing blood flow. These alpha 2 receptors are known as autoreceptors which provide negative feedback in neurotransmission (in this case, the vasoconstriction effects of adrenaline). Central alpha agonists, such as clonidine ...
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
But the blood pressure benefits of this breakfast don’t stop there. Smoked salmon provides a healthy dose of omega-3 fats, another key nutrient for lower blood pressure. This bowl also boasts 15 ...
Interactions with such drugs can cause either an unintended increase in blood pressure or potentiate an increase in blood pressure. [2] Finally, in drugs with both alpha and beta blocking properties, such as carvedilol and labetalol, interactions with other alpha or beta blockers can exaggerate a decrease in blood pressure. [2]
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Clonidine, sold under the brand name Catapres among others, is an α 2A-adrenergic receptor agonist [12] medication used to treat high blood pressure, ADHD, drug withdrawal (e.g., alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. [13]
Additionally, Cochrane reviews have found that for older individuals with moderate to high cardiovascular risk, the benefits of trying to achieve a lower-than-standard blood pressure target (at or below 140/90 mmHg) are outweighed by the risk associated with the intervention. [118]