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Prior to surgery, cytotoxic agents such as oxaliplatin given systemically for colorectal metastasis, or chemoembolization for hepatocellular carcinoma can significantly decrease the size of the tumor bulk, allowing then for resections which would remove a segment or wedge portion of the liver only.
Studies from the late 2000s obtained higher survival rates ranging from 67% to 91%. [62] Other estimates of 5 year survival after liver transplantation range from 60 to 60% with a 50% survival rate at 10 years. [6] The risk of HCC recurrence after liver transplantation is less than 15%. [6]
Liver transplantation is a potential treatment for acute or chronic conditions which cause irreversible and severe ("end-stage") liver dysfunction. [4] Since the procedure carries relatively high risks, is resource-intensive, and requires major life modifications after surgery, it is reserved for dire circumstances.
The family of 70-year-old William Bryan claims surgeon Thomas Shaknovsky removed his liver and not his spleen during a procedure he did not survive.
In terms of mortality, the 5-year survival rate for liver and intrahepatic bile duct cancers in the United States is 19.6%. [79] In the United States, there is an estimated 1% chance of getting liver cancer across the lifespan, which makes this cancer relatively rare. [79] Despite the low number of cases, it is one of the top causes of cancer ...
Even when surgery is successful the 5-year survival is typically less than 50%. [6] Cholangiocarcinoma is rare in the Western world, with estimates of it occurring in 0.5–2 people per 100,000 per year. [1] [6] Rates are higher in Southeast Asia where liver flukes are common. [5] Rates in parts of Thailand are 60 per 100,000 per year. [5]
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