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The average age at which puberty begins may be affected by ethnicity as well. For example, the average age of menarche in various populations surveyed has ranged from 12 [58] [59] [60] to 18 years. The earliest average onset of puberty is for African-American females and the latest average onset for high altitude subsistence populations in Asia.
Notable modern pop cultural figures with growth hormone deficiency include actor and comedian Andy Milonakis, who has the appearance and voice of an adolescent boy despite being in his 40s. [ 29 ] [ 30 ] Argentine footballer Lionel Messi was diagnosed at age 10 with growth hormone deficiency and was subsequently treated. [ 31 ]
The adolescent growth spurt is a rapid increase in the individual's height and weight during puberty resulting from the simultaneous release of growth hormones, thyroid hormones, and androgens. [37]: 55–56 Males experience their growth spurt about two years later, on average, than females.
Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical ...
Puberty is considered delayed when the child has not begun puberty when two standard deviations or about 95% of children from similar backgrounds have. [7] [8] [9]In North American girls, puberty is considered delayed when breast development has not begun by age 13, when they have not started menstruating by age 15, [2] and when there is no increased growth rate. [8]
Psychosocial short stature (PSS) is a growth disorder that is observed between the ages of 2 and 15, caused by extreme emotional deprivation or stress.. The symptoms include decreased growth hormone (GH) and somatomedin secretion, very short stature, weight that is inappropriate for the height, and immature skeletal age.
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