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Elevated CEA levels should return to normal after successful surgical removal of the tumor and can be used in follow up, especially of colorectal cancers. [15] CEA elevation is known to be affected by multiple factors. It varies inversely with tumor grade; well-differentiated tumors secrete more CEA.
n/a Ensembl ENSG00000105388 n/a UniProt P06731 n/a RefSeq (mRNA) NM_001291484 NM_001308398 NM_004363 n/a RefSeq (protein) NP_001278413 NP_001295327 NP_004354 n/a Location (UCSC) Chr 19: 41.71 – 41.73 Mb n/a PubMed search n/a Wikidata View/Edit Human Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (C luster of D ifferentiation 66e), is a member of the ...
Tumor markers can be molecules that are produced in higher amounts by cancer cells than normal cells, but can also be produced by other cells from a reaction with the cancer. [ 2 ] The markers can't be used to give patients a diagnosis but can be compared with the result of other tests like biopsy or imaging.
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19.
The National Cancer Institute (NCI), in particular, defines biomarker as a: “A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition.
Biomarkers found in blood, urine, or body tissues that can be introduced or elevated by the presence of one or more types of cancer. Pages in category "Tumor markers" The following 45 pages are in this category, out of 45 total.
A reference range is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% prediction interval). [2] It is determined by collecting data from vast numbers of laboratory tests.
CA 242 is a tumor marker for sialylated Lewis carbohydrates associated with adenocarcinomas and e-selectin-mediated metastatic risk. [1] [2] [3] It is commonly tested along with CEA, CA19-9, and CA242 for detecting pancreatic cancer. [4] The specificity of CA 242 is higher than similar markers.