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  2. Progesterone (medication) - Wikipedia

    en.wikipedia.org/wiki/Progesterone_(medication)

    Vaginal progesterone suppositories were first studied in women by Robert Greenblatt in 1954. [282] [190] [283] Shortly thereafter, vaginal progesterone suppositories were introduced for medical use under the brand name Colprosterone in 1955. [284] [190] Rectal progesterone suppositories were first studied in men and women by Christian Hamburger ...

  3. Suppository - Wikipedia

    en.wikipedia.org/wiki/Suppository

    Rectal suppositories are intended for localized or systemic action to relieve pain, constipation, irritation, inflammation, nausea and vomiting, fever, migraines, allergies, and sedation. [7] [8] If they cause inflammation, chronic use of suppositories may cause rectal stricture, [9] but overall this is a safe method of drug delivery. [10]

  4. Estriol (medication) - Wikipedia

    en.wikipedia.org/wiki/Estriol_(medication)

    Administration of a rectal suppository containing 100 mg estriol resulted in estriol levels in pregnant women at term increasing by about 53%. [87] Estriol levels at term are normally between 5,000 and 20,000 pg/mL, which suggests that estriol levels may have increased following the suppository by about 5,000 to 10,000 pg/mL (precise levels ...

  5. B&O Supprettes - Wikipedia

    en.wikipedia.org/wiki/B&O_Supprettes

    Each B&O Supprettes suppository #15 A contains 16.2 mg (1/4 grain) of belladonna and 30 mg (1/2 grain) of opium. Each B&O Supprettes suppository #16 A contains 16.2 mg of belladonna and 60 mg (1 grain) of opium. The usual dose is one suppository rectally once or twice daily PRN - (as needed), not to exceed four Supprettes in a 24-hour period. [1]

  6. Misoprostol - Wikipedia

    en.wikipedia.org/wiki/Misoprostol

    Misoprostol should not be taken by pregnant women with wanted pregnancies to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.

  7. Prostaglandin E2 - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_E2

    The hospital had run out of Cervidil which is a 10 mg endocervical insert and the provider decided to use half of a 20 mg Prostin E2 vaginal suppository. Cervidil delivers the drug at a constant rate and can be removed as necessary while Prostin E2 dissolves immediately and can not be removed.