Search results
Results From The WOW.Com Content Network
UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator-evaluated computational analysis. The aim of UniProtKB/Swiss-Prot is to provide all known relevant information about a particular protein.
The latter conveniently allows users to obtain the amino acid sequences and domain boundaries from UniProtKB/Swiss-Prot and UniProtKB/TrEMBL databases in either embl, genbank or fasta format. [16] By clicking the external database link, users can get this information for the domain-containing protein found in other species.
The UniProtKB accession number P39394 indicates the general structure of the SymE toxin in Escherichia coli. [ 1 ] [ 7 ] In the SWISS-MODEL SymE theoretical model, the α {\displaystyle \alpha } -helix contains amino acids G 44, Q 45, W 46, L 47, E 48, A 49, and A 50.
Only signatures deemed to be of sufficient quality are integrated into InterPro. As of version 81.0 (released 21 August 2020) InterPro entries annotated 73.9% of residues found in UniProtKB with another 9.2% annotated by signatures that are pending integration. [5] The coverage of UniProtKB residues by InterPro entries as of InterPro version 81 ...
For each family, a representative subset of sequences are aligned into a high-quality seed alignment. Sequences for the seed alignment are taken primarily from pfamseq (a non-redundant database of reference proteomes) with some supplementation from UniprotKB. [15] This seed alignment is then used to build a profile hidden Markov model using ...
Schematic representation of the three top levels of the CATH classification scheme. [2]The CATH Protein Structure Classification database is a free, publicly available online resource that provides information on the evolutionary relationships of protein domains.
The NCBI assigns a unique identifier (taxonomy ID number) to each species of organism. [5] The NCBI has software tools that are available through web browsers or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds.
In humans, the main isoform of POMGnT1 contains 660 amino acids whose sequence yields a calculated molecular mass of 75,252 Da (UniProtKB Q8WZA1). The POMGNT1 mRNA and its encoded protein is expressed in the neural retina of all mammals studied. POMGnT1 locates in the cytoplasmic fraction in the mouse retina, where it concentrates in the Golgi ...