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Alphacoronavirus amsterdamense [1] ( also called Human coronavirus NL63 abbreviated HCoV-NL63) is a species of coronavirus, specifically a Setracovirus from among the Alphacoronavirus genus. It was identified in late 2004 in patients in the Netherlands by Lia van der Hoek and Krzysztof Pyrc [2] using a novel virus discovery method VIDISCA. [3]
The transmission of COVID-19 is the passing of coronavirus disease 2019 from person to person. COVID-19 is mainly transmitted when people breathe in air contaminated by droplets/aerosols and small airborne particles containing the virus. Infected people exhale those particles as they breathe, talk, cough, sneeze, or sing.
It was possible to confirm the nature of the pathogen as a filter-passing virus as it was susceptible to ether treatment (indicating a lipid-enveloped virus), able to induce cold in antibiotic-treated volunteers (indicating it was not a bacterium), and grown in human-embryo-trachea epithelial cell culture.
The first demonstration of phagocytosis as a property of leukocytes, the immune cells, was from the German zoologist Ernst Haeckel. [14] [15] In 1846, English physician Thomas Wharton Jones had discovered that a group of leucocytes, which he called "granule-cell" (later renamed and identified as eosinophil [16]), could change shape, the phenomenon later called amoeboid movement.
Viral phylodynamics is the study of how epidemiological, immunological, and evolutionary processes act and potentially interact to shape viral phylogenies. [1] Since the term was coined in 2004, research on viral phylodynamics has focused on transmission dynamics in an effort to shed light on how these dynamics impact viral genetic variation.
Phagocytes are usually not bound to any particular organ but move through the body interacting with the other phagocytic and non-phagocytic cells of the immune system. They can communicate with other cells by producing chemicals called cytokines , which recruit other phagocytes to the site of infections or stimulate dormant lymphocytes . [ 53 ]
Waterborne transmission- leaving a host, infecting the water, and being consumed in a new host Poliovirus is an example for this [36] Sit-and-wait-transmission- the virus is living outside a host for long periods of time The smallpox virus is also an example for this [36] Virulence, or the harm that the virus does on its host, depends on ...
Infectious bronchitis virus (IBV), a type of coronavirus, causes avian infectious bronchitis. [131] The virus is of concern to the poultry industry because of the high mortality from infection, its rapid spread, and its effect on production. [127] The virus affects both meat production and egg production and causes substantial economic loss. [132]