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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
Tolerable daily intake (TDI) refers to the daily amount of a chemical contaminant that has been assessed safe for human being exposure on long-term basis (usually whole lifetime). [1] TDI specifically occurs to chemicals that humans are exposed to unintentionally or as a contaminant, [ 1 ] where acceptable daily intake refers to chemicals that ...
The recommended adequate intake of sodium is 1,500 milligrams (3.9 g salt) per day, and people over 50 need even less." [13] The Daily Value for potassium, 4,700 mg per day, was based on a study of men who were given 14.6 g of sodium chloride per day and treated with potassium supplements until the frequency of salt sensitivity was reduced to 20%.
The FDA’s previous safety limit, known as the acceptable daily intake, for red No. 3 was 2.5 milligrams per kilogram of body weight per day,” she explained. A step toward improving public health
Estimating or calculating the dietary exposure to a given chemical or contaminant allows a comparison to a relevant health standard such as the acceptable daily intake(ADI), the acute reference dose (ARfD) or a reference dose (RfD), or a level known to cause adverse effects in animal or human health studies. [2]
The FDA’s acceptable daily intake of aspartame is 50 mg per kilogram of body weight. A 12-ounce can of Diet Coke has about 180 mg of aspartame, meaning a person weighing 68 kg ...
"With a can of diet soft drink containing 200 or 300 mg of aspartame, an adult weighing (154 pounds) would need to consume more than 9–14 cans per day to exceed the acceptable daily intake ...
The JECFA makes a distinction between acceptable intakes and tolerable intakes. Tolerable is used to demonstrate permissibility, not acceptability. [3] Substances such as food additives, veterinary drugs, and pesticides that can be controlled in the food supply relatively easily are assessed an acceptable daily intake, or ADI.