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A number of such organisms are currently being investigated for their use as treatment, including: Trichuris suis ova, [6] [7] commonly known as pig whipworm eggs; Necator americanus, [8] commonly known as hookworms; Trichuris trichiura ova, [9] commonly referred to as human whipworm eggs; and Hymenolepis diminuta, commonly known as rat tapeworm.
Life cycle of Trichuris trichiura inside and outside the human body. The female T. trichiura produces 2,000–10,000 single-celled eggs per day. [3] Eggs are deposited from human feces to soil where, after two to three weeks, they become embryonated and enter the "infective" stage.
Trichuriasis, also known as whipworm infection, is an infection by the parasitic worm Trichuris trichiura (whipworm). [2] If the infection is only with a few worms, there are often no symptoms. [ 1 ] In those who are infected with many worms, there may be abdominal pain , fatigue and diarrhea . [ 1 ]
A novel drug tribendimidine, which was approved in China by the CCDC for human use in 2004, has been subjected to clinical trials showing that they are highly effective against major human flukes, ascaris (>90% cure rate) and hookworm (>82%); however with low cure rate for whipworm (<37%). [31]
The soil-transmitted helminths (A. lumbricoides, T. trichiura, N. americanus, A. duodenale), schistosomes, and filarial worms collectively infect more than a quarter of the human population worldwide at any one time, far surpassing HIV and malaria together. [35] [37] Schistosomiasis is the second most prevalent parasitic disease of humans after ...
Therefore, for the same amount of money, mass deworming can treat more people more cost-effectively than selective deworming. [5] Mass deworming is one example of mass drug administration. [3] Mass deworming of children can be carried out by administering mebendazole and albendazole which are two types of anthelmintic drug. [5]
Trichuris suis is a whipworm; the variations in thickness of the anterior and posterior segments give the parasite the characteristic "whip-like" appearance.Adult females measure 6 to 8 cm and adult males 3 to 4 cm. T. suis eggs are oval (60 × 25 μm) and yellow-brown with bipolar plugs. [1]
The human whipworm, a parasitic worm. Because Hepatitis C virus (HCV) and the parasitic worm Schistosoma (the bloodfluke) are relatively common in developing countries, there are many cases where both are present in the human body. [21] According to Kamal, bloodflukes have been adequately shown to worsen HCV. [21]