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Oxcarbazepine, sold under the brand name Trileptal among others, is a medication used to treat epilepsy. [3] [5] For epilepsy it is used for both focal seizures and generalized seizures. [6] It has been used both alone and as add-on therapy in people with bipolar disorder who have had no success with other treatments. [7] [5] It is taken by ...
Pentylenetetrazol has been used experimentally to study seizure phenomena and to identify pharmaceuticals that may control seizure susceptibility. For instance, researchers can induce status epilepticus in animal models. Pentylenetetrazol is also a prototypical anxiogenic drug and has been extensively used in animal models of anxiety.
Both newer and older drugs are generally equally effective in new onset epilepsy. [42] The newer drugs tend to have fewer side effects. [42] For newly diagnosed partial or mixed seizures, there is evidence for using gabapentin, lamotrigine, oxcarbazepine or topiramate as monotherapy. [42]
Most of these patients were using the only effective drug then available, bromide, which had terrible side effects and limited efficacy. On phenobarbital, their epilepsy was much improved: The worst [clarification needed] patients had fewer and lighter seizures and some patients became seizure-free. In addition, they improved physically and ...
There are many hazards that people with epilepsy, including those whose seizures are fully controlled by medication, face in the workplace. Those with active seizures face the obvious risk of loss of consciousness or muscle control, and those with side effects face diminished concentration or physical strength. Some of the hazards include: [5]
In uncontrolled studies, nitrazepam has shown effectiveness in infantile spasms and is sometimes considered when other anti-seizure drugs have failed. [9] However, drowsiness, hypotonia, and most significantly tolerance to anti-seizure effects typically develop with long-term treatment, generally limiting Nitrazepam to acute seizure management ...