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116849 Ensembl ENSG00000127318 ENSMUSG00000090461 UniProt Q9GZX6 Q9JJY8 RefSeq (mRNA) NM_020525 NM_054079 RefSeq (protein) NP_065386 NP_473420 Location (UCSC) Chr 12: 68.25 – 68.25 Mb Chr 10: 118.13 – 118.13 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-22 (IL-22) is a protein that in humans is encoded by the IL22 gene. Structure IL-22 is an α-helical cytokine. IL ...
Interleukin 9 (IL-9) [30] is a cytokine that supports IL-2 independent and IL-4 independent growth of helper T cells. Early studies had indicated that Interleukin 9 and 7 seem to be evolutionary related [ 31 ] and Pfam, InterPro and PROSITE entries exist for interleukin 7/interleukin 9 family.
The interleukin-1 superfamily has 11 members, which have similar gene structure, although originally it contained only four members IL-1α, IL-1β, IL-1Ra and IL-18. After discovery of another 5 members the updated nomenclature was generally accepted which included all members of IL-1 cytokine family. The old IL-1 members were renamed to IL-1F1 ...
Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene.IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain and the common gamma chain (gamma-C, CD132).
16878 Ensembl ENSG00000128342 ENSMUSG00000034394 UniProt P15018 P09056 RefSeq (mRNA) NM_001257135 NM_002309 NM_001039537 NM_008501 RefSeq (protein) NP_001244064 NP_002300 NP_001034626 NP_032527 Location (UCSC) Chr 22: 30.24 – 30.25 Mb Chr 11: 4.21 – 4.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that ...
Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. [5] [6] In general, Interleukin 1 is responsible for the production of inflammation, as well as the promotion of fever and sepsis. IL-1α inhibitors are being developed to interrupt those processes ...
Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA gene. [5] [6] [7] Interleukin-14 is a cytokine that controls the growth and proliferation of both normal and cancerous B cells. [8] This molecule was also recently designated taxilin. [9]
[8] [9] It was developed as a recombinant protein (rhIL-11) as the drug substance oprelvekin. The human IL-11 gene, consisting of 5 exons and 4 introns, is located on chromosome 19, [6] and encodes a 23 kDa protein. IL-11 is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130.