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The American Society of Health-System Pharmacists (ASHP) reported that 323 "active medication shortages" were reported in January–March 2024. As a result of drug scarcity, many healthcare systems were forced to either ration out essential drugs, triage patients based on the severity of their condition and their need for the drug, or both.
For example, under a 3-tier formulary, the first tier typically includes generic drugs with the lowest cost sharing (e.g., 10% coinsurance), the second includes preferred brand-name drugs with higher cost sharing (e.g., 25%), and the third includes non-preferred brand-name drugs with the highest cost-sharing (e.g., 40%).
Medication costs can be the selling price from the manufacturer, that price together with shipping, the wholesale price, the retail price, and the dispensed price. [3]The dispensed price or prescription cost is defined as a cost which the patient has to pay to get medicines or treatments which are written as directions on prescription by a prescribers. [4]
[38] low income families tended to have higher prescription drug expenses during the year: 18.9% of poor households paid more than $4,724 compared to 13.2% and 12.5% who had prescription drug expenses between $2,084–$4,723 and $1–2,083, respectively. [38]
A modification of Lagged-Fibonacci generators. A SWB generator is the basis for the RANLUX generator, [19] widely used e.g. for particle physics simulations. Maximally periodic reciprocals: 1992 R. A. J. Matthews [20] A method with roots in number theory, although never used in practical applications. KISS: 1993 G. Marsaglia [21]
Pro Evolution Soccer 2019 (officially abbreviated as PES 2019, also known in Japan as Winning Eleven 2019) is the 18th installment in the game series. PES 2019 is the first PES in 10 years not to feature the UEFA Champions League, UEFA Europa League and UEFA Super Cup license after Konami lost the rights to EA Sports.
PES 2020 is the last game in the series to use Kojima Productions's Fox Engine. It is also the last installment in the franchise to use the PES name and branding as the following installment was just named eFootball and is free to play. [3] [4] The mobile version reached 300 million downloads by June 2020. [5]
The update was delayed and the release postponed to November 2021. [7] Konami then launched the update 0.9.1 on 5 November, [8] and announced that the 1.0 update release was delayed until Spring 2022. [9] Version 1.0.0 of eFootball 2022 was finally announced on 6 April 2022, with release date on 14 April 2022. [10]