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Leontiasis ossea, also known as leontiasis, lion face or lion face syndrome, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones. It is not a disease in itself, but a symptom of other diseases, including Paget's disease , fibrous dysplasia , hyperparathyroidism and renal osteodystrophy .
Leonine facies is a facies that resembles that of a lion. It is seen in multiple conditions and has been classically described for lepromatous leprosy as well as Paget's disease of bone. It is a dermatological symptom, with characteristic facial features that are visible on presentation, and is useful for focusing on differential diagnosis.
Pitt–Hopkins syndrome Beta thalassemia is associated with distinctive facial features due to ineffective erythropoiesis. The ineffective erythropoiesis causes marrow hyperplasia or expansion and bony changes, including the bones of the face; this causes craniofacial protrusions.
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A Tennessee man has a rare disorder that causes faces to appear distorted in shape, size, texture or color. To him, images show, they look demonic. ... Some people "have seen face distortions ...
Prosopometamorphopsia (PMO), [1] also known as demon face syndrome, [2] is a neurological disorder characterized by altered perceptions of faces. In the perception of a person with the disorder, facial features are distorted in a variety of ways including drooping, swelling, discoloration, and shifts of position.
[7] [8] [9] (The name of this protein was inspired by the Sonic the Hedgehog video game character and is part of an idiosyncratic naming tradition in molecular biology research.) [10] [11] SHH and its corresponding genes have been found to play an important role in signaling craniofacial patterning during embryonic development.
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