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The World Health Organization (WHO) does not recommend the use of combined oral contraceptive pills in women with breast cancer. [41] [97] Since combined oral contraceptive pills contain both estrogen and progestin, they are not recommended to be used in those with hormonally-sensitive cancers, including some types of breast cancer.
Between 2015 and 2017, 64.9% of women ages 15–49 in the United States were using contraception, and of those 12.6% were using the oral contraceptive pill. [46] There are approximately 100 million users of combined oral contraceptives worldwide, with use being more common in Western Europe, Northern Europe, and the United States. [47]
Breast cancer risk: How do IUDs compare to contraceptive pills? After reviewing this research, Nora J. Doty, MD, a complex family planning specialist in the Department of Obstetrics and Gynecology ...
They concluded that: "Overall, there was no evidence of an increased risk of breast cancer". [53] Recent anxieties about the contribution of progestogens to the increased risk of breast cancer associated with HRT in postmenopausal women such as found in the WHI trials [54] have not spread to progestogen-only contraceptive use in premenopausal ...
[82] [107] However, doses of 1 to 5 mg megestrol acetate were previously used in combined birth control pills in combination with the estrogen ethinylestradiol or mestranol. [8] [9] [32] Megestrol acetate is an effective contraceptive by itself at dosages of 0.35 to 0.5 mg/day, but is not effective at a dosage of 0.25 mg/day. [7]
Long-term studies of users of DMPA have found slight or no increased overall risk of breast cancer. However, the study population did show a slightly increased risk of breast cancer in recent users (DMPA use in the last four years) under age 35, similar to that seen with the use of combined oral contraceptive pills. [73
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