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Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
The nutrient, also called calciferol, is critical for the health of your immune, nervous, and musculoskeletal systems, too. But because few foods naturally contain vitamin D, dietary supplements ...
Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2.Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources.
Transcription of these genes is stimulated and produces greater levels of the proteins that mediate the effects of vitamin D. [3] Some reactions of the cell to calcitriol appear to be too fast for the classical VDRE transcription pathway, leading to the discovery of various non-genomic actions of vitamin D.
Vitamin D3 needs for the average adult between the ages 19 and 70 years old is 600 IU (15 mcg) per day, says Pelitera. “This includes foods, for example, 1 cup of fortified milk contains about ...
The reason for gradually increasing dosages, per Alan, is to lower the risk of side effects. “Too much too fast can cause unpleasant side effects, such as nausea and constipation,” Alan says.