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Marketed as Curanail, Loceryl, Locetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine hydrochloride as the active ingredient. It is used to treat onychomycosis (fungal infection of the toe- and fingernails). Amorolfine 5% nail lacquer in once-weekly or twice-weekly applications was shown in ...
In addition to other formulations, ciclopirox is used in lacquers for topical treatment of onychomycosis (fungal infections of the nails). A meta-analysis of the six trials of nail infections available in 2009 concluded that they provided evidence that topical ciclopirox had poor cure rates, and that amorolfine might be substantially more effective, but more research was required.
[2] [5] Trimming the affected nails when on treatment also appears useful. [2] There is a ciclopirox-containing nail polish, but there is no evidence that it works. [2] The condition returns in up to half of cases following treatment. [2] Not using old shoes after treatment may decrease the risk of recurrence. [3]
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Miconazole is a widely used topical antifungal medication for the treatment of many fungal infections, namely skin infections, nail infections and vaginal candidiasis. The drug is usually formulated in creams, powders and sprays. However, it is suggested that patients developing acute porphyrias should avoid using this drug.
In a study from 2002, researchers found that a 5% lidocaine-prilocaine cream increased the average pre-climax period by 8.7 minutes (+/- 1.7 minutes) when applied before intimacy.