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Cerebellar cognitive affective syndrome (CCAS), also called Schmahmann's syndrome [1] is a condition that follows from lesions (damage) to the cerebellum of the brain. It refers to a constellation of deficits in the cognitive domains of executive function , spatial cognition , language , and affect resulting from damage to the cerebellum.
[31] [32] In particular, the cerebellar cognitive affective syndrome or Schmahmann's syndrome [33] has been described in adults [34] and children. [35] Estimates based on functional mapping of the cerebellum using functional MRI suggest that more than half of the cerebellar cortex is interconnected with association zones of the cerebral cortex ...
A common motor syndrome that causes dysmetria is cerebellar motor syndrome, which also marked by impairments in gait (also known as ataxia), disordered eye movements, tremor, difficulty swallowing and poor articulation. [5] As stated above, cerebellar cognitive affective syndrome (CCAS) also causes dysmetria.
Ataxia (from Greek α- [a negative prefix] + -τάξις [order] = "lack of order") is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements, that indicates dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum.
Cerebellar cognitive affective syndrome; Cerebellar stroke syndrome; Corneal-cerebellar syndrome; D. Dandy–Walker malformation; G. Gómez–López-Hernández ...
When lesions occur in the association areas linked to the cerebellum by corticopontocerebellar fibres, the cognitive affective syndrome may occur. This results in cognitive defects in the form of diminished reasoning power, inattention, grammatical errors in speech, poor spatial sense, and patchy memory loss. [14]
A "cerebellar cognitive affective syndrome" has been described resulting in personality change and how the person shows emotions. [39] Lateral prefrontal cortex – Using our emotions, the lateral prefrontal cortex is responsible for helping us reach our goals by suppressing harmful behaviors or selecting productive ones. [40]
Cerebellar signs usually involve balance and coordination, and may include: [citation needed] cerebellar ataxia a gait with a broad base; the patient falters to the side of the lesion ( ataxia ) inability to coordinate fine motor activities ( intention tremor ), e.g. "past-pointing" (pointing beyond the finger in the finger-nose test)