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The outcomes of DIAS-3 and DIAS-4 studies should tell whether desmoteplase is a breakthrough treatment for acute ischaemic stroke. In June 2014, Lundbeck published a press release about the DIAS-3 study revealing neutral results in an intention-to-treat analysis. [9]
Doctors may have made a revolutionary breakthrough in the way we treat stroke patients. Patients in the trial study regained the ability to talk, walk and live normal lives, all thanks to a ...
A barrier to stroke rehabilitation over the years has been the difficulty of implementing treatment protocol outside of a controlled environment in real-world settings like clinics.
A breakthrough therapy designation can be assigned to a drug if "it is a drug which is intended alone or in combination with one or more other drugs to treat a serious or life threatening disease or condition" and if the preliminary clinical evidence indicates that the drug may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints, such as ...
Though safety has been established through previous clinical trials, there is ongoing debate about whether this is an effective treatment for ischemic stroke, and significant ongoing discussion between emergency physicians, neurologists and pharmacists about whether this treatment should be used for that indication.
The former patient was a commercial real estate broker. He now suffers memory issues and cannot care for himself.