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  2. Tocilizumab - Wikipedia

    en.wikipedia.org/wiki/Tocilizumab

    Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID‑19, and systemic sclerosis-associated interstitial lung disease (SSc-ILD).

  3. Anti-interleukin-6 - Wikipedia

    en.wikipedia.org/wiki/Anti-interleukin-6

    The first approved medication in this class, tocilizumab (Actemra), is an antibody directed against the IL6-receptor. [8] The second, siltuximab (Sylvant), is directed against IL-6 itself. [ 1 ] [ 9 ] Siltuximab is approved for treatment of human immunodeficiency virus-negative and HHV-8 -negative patients with multicentric Castleman's disease .

  4. Roche Starts Study on Actemra with Gilead's Drug for ... - AOL

    www.aol.com/news/roche-starts-study-actemra-gi...

    Roche (RHHBY) commences a phase III study on Actemra with Gilead's remdesivir in hospitalized patients with severe COVID-19 pneumonia.

  5. Therapeutic drug monitoring - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_drug_monitoring

    Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range , i.e. drugs that can easily be under- or overdosed. [ 1 ]

  6. Risk Evaluation and Mitigation Strategies - Wikipedia

    en.wikipedia.org/wiki/Risk_Evaluation_and...

    Risk Evaluation and Mitigation Strategies (REMS) is a program of the US Food and Drug Administration for the monitoring of medications with a high potential for serious adverse effects. REMS applies only to specific prescription drugs, but can apply to brand name or generic drugs. [ 1 ]

  7. Pharmacovigilance - Wikipedia

    en.wikipedia.org/wiki/Pharmacovigilance

    Pharmacovigilance (PV, or PhV), also known as drug safety, is the pharmaceutical science relating to the "collection, detection, assessment, monitoring, and prevention" of adverse effects with pharmaceutical products. [1]: 7 The etymological roots for the word "pharmacovigilance" are: pharmakon (Greek for drug) and vigilare (Latin for to keep watch

  8. Sanofi (SNY) Q4 2024 Earnings Call Transcript - AOL

    www.aol.com/finance/sanofi-sny-q4-2024-earnings...

    Image source: The Motley Fool. Sanofi (NASDAQ: SNY) Q4 2024 Earnings Call Jan 30, 2025, 9:00 a.m. ET. Contents: Prepared Remarks. Questions and Answers. Call ...

  9. Disease-modifying antirheumatic drug - Wikipedia

    en.wikipedia.org/wiki/Disease-modifying_anti...

    Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...

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